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Article

Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome.

Stem cell research & therapy - 20 Mar 2017

Clark Kaitlin C, Fierro Fernando A, Ko Emily Mills, Walker Naomi J, Arzi Boaz, Tepper Clifford G, Dahlenburg Heather, Cicchetto Andrew, Kol Amir, Marsh Lyndsey, Murphy William J, Fazel Nasim, Borjesson Dori L

Abstract excerpt

BACKGROUND: Adipose-derived mesenchymal stem cells (ASCs) are a promising cell therapy to treat inflammatory and immune-mediated diseases. Development of appropriate pre-clinical animal models is critical to determine safety and attain early efficacy data for the most promising therapeutic candidates. Naturally occurring diseases in cats already serve as valuable models to inform human clinical trials in...

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Identifiers

PMID: 28320483
DOI: 10.1186/s13287-017-0528-z
PMCID: PMC5360077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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