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Article

Amplification of <i>PRKCI</i>, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma

7 Nov 2007

Abstract excerpt

DNA amplification is one of the mechanisms to activate genes that are implicated in neoplastic transformation and gain of chromosome band 3q26 is a common event in squamous cell carcinomas. The aim of the present work was to identify the specific target gene from four candidates (MDS1, PRKCI, ECT2, and PIK3CA) located on 3q26 amplification in esophageal squamous cell carcinomas (ESCCs). To assess the prevalence...

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PMID: 17990328
DOI: 10.1002/gcc.20514

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