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Article

Identification of <i>PAK4</i> as a putative target gene for amplification within 19q13.12‐q13.2 in oral squamous‐cell carcinoma

23 Jun 2009

Abstract excerpt

Amplification of chromosomal DNA is thought to be one of the mechanisms activating cancer-related genes in tumors. To identify the most likely target for amplification in the region 19q13.12-q13.2, detected previously in SKN-3 cells by a genome-wide screening of DNA copy-number aberrations in a panel of oral squamous-cell carcinoma (OSCC) cell lines, we determined the extent of the amplicon, analyzed a panel of...

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PMID: 19594544
DOI: 10.1111/j.1349-7006.2009.01252.x

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