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Article

Filaggrin polymorphism P478S, IgE level, and atopic phenotypes.

The British journal of dermatology - 1 Apr 2011

Wang I J, Lin T J, Kuo C F, Lin S L, Lee Y L, Chen P C

Abstract excerpt

BACKGROUND: Whether environmental exposures may modulate the effect of the skin barrier gene on atopic dermatitis (AD) remains to be elucidated. OBJECTIVES: To determine whether filaggrin (FLG) variants can serve as a predictor for atopic disorders in Chinese individuals and if allergen exposures may modify the effect of FLG variants on AD by total IgE levels. METHODS: In total, 116 children aged 2-5years with AD...

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Source

Identifiers

PMID: 21219289
DOI: 10.1111/j.1365-2133.2011.10212.x

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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