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Article

An ENU-induced mutation in the Ankrd11 gene results in an osteopenia-like phenotype in the mouse mutant Yoda.

Physiological genomics - 19 Feb 2008

Barbaric Ivana, Perry Mark J, Dear T Neil, Rodrigues Da Costa Alexandra, Salopek Daniela, Marusic Ana, Hough Tertius, Wells Sara, Hunter A Jackie, Cheeseman Michael, Brown Steve D M

Abstract excerpt

The mechanisms that regulate bone mass are important in a variety of complex diseases such as osteopenia and osteoporosis. Regulation of bone mass is a polygenic trait and is also influenced by various environmental and lifestyle factors, making analysis of the genetic basis difficult. As an effort toward identifying novel genes involved in regulation of bone mass, N-ethyl-N-nitrosourea (ENU) mutagenesis in mice...

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Identifiers

PMID: 17986521
DOI: 10.1152/physiolgenomics.00116.2007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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