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Article

Expression of the Lyst(beige) mutation is atheroprotective in chow-fed apolipoprotein E-deficient mice.

Journal of lipid research - 1 Feb 2008

Petrovan Ramona J, Yuan Yuan, Curtiss Linda K

Abstract excerpt

Lyst(beige) mice crossed with hyperlipidemic low density lipoprotein receptor-deficient mice (BgLDLr(-/-)) display increased lesion area and a more stable lesion morphology. To verify that the beige phenotype is not unique to LDLr(-/-) mice, we examined atherosclerosis in beige, apolipoprotein E-deficient mutant mice (BgApoE(-/-)). Severe diet-induced hyperlipidemia in BgApoE(-/-) mice resulted in increased...

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Identifiers

PMID: 17982137
DOI: 10.1194/jlr.M700410-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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