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Article

The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2008

Ramsay Andrew J, Reid Janet C, Velasco Gloria, Quigley James P, Hooper John D

Abstract excerpt

Matriptase-2 (also known as TMPRSS6) is a recently identified member of the type II transmembrane serine protease (TTSP) family. Structurally this enzyme contains a short cytoplasmic amino terminal tail, a transmembrane region, a stem region containing two CUB domains and three LDL receptor class A domains, and at the carboxy terminal a trypsin-like serine protease domain. The matriptase-2 gene and encoded...

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Source

Identifiers

PMID: 17981570
DOI: 10.2741/2702

Genes

TMPRSS6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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