Article
Cloning and characterization of TMPRSS6, a novel type 2 transmembrane serine protease.
Molecules and cells - 30 Apr 2005
Park Tae Joo, Lee Yong Jae, Kim Hye Jin, Park Hye Gyeong, Park Woo Jin
Abstract excerpt
We have identified TMPRSS6, a novel type 2 transmembrane serine protease. TMPRSS6 possesses all the signature motifs of the family of transmembrane serine proteases (TMPRSSs), including a transmembrane domain, an LDL receptor class A (LDLRA) domain, a scavenger receptor cysteine-rich (SRCR) domain, and a serine protease domain. The substrate specificity of TMPRSS6 is slightly different from those of other TMPRSS...
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