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Article

Recognition of allo-peptide is governed by novel anchor imposition and limited variations in TCR contact residues.

Molecular immunology - 1 Mar 2008

Reinbold Corbett J A, Malarkannan Subramaniam

Abstract excerpt

Immune specificity of a T cell is determined by the TCR contact residues exposed on the antigenic peptide/MHC complex. Naturally processed, biallelic epitopes from H7 minor histocompatibility (mH) antigen vary in position 7 (p7) from aspartic acid (D) to a glutamic acid (E), which differ by an additional methylene (-CH(2)) in the side chain. Here, we show that this variation generates a strong anti-H7a or...

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Identifiers

PMID: 17981332
DOI: 10.1016/j.molimm.2007.09.017
PMCID: PMC3835348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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