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Article

Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2012

Kiyohara Chikako, Horiuchi Takahiko, Takayama Koichi, Nakanishi Yoichi

Abstract excerpt

BACKGROUND: Several components of overall lung carcinogenesis, carcinogen metabolic and DNA repair pathways may be involved in individual genetic susceptibility to lung cancer. METHODS: We evaluated the role of cytochrome P450 (CYP) 1A1 rs4646903 and rs104894, glutathione S-transferase (GST) M1 and GSTT1 deletion polymorphisms, GSTP1 rs1695, x-ray repair, excision repair cross-complementing group 2 (ERCC2)...

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Source

Identifiers

PMID: 22525558
DOI: 10.1097/JTO.0b013e31824de30f

Genes

ERCC2
GSTM1
GSTP1
GSTT1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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