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Isolation and Molecular Characterization of Cancer Stem Cells in MMTV-<i>Wnt-1</i> Murine Breast Tumors

1 Nov 2007

Abstract excerpt

In human breast cancers, a phenotypically distinct minority population of tumorigenic (TG) cancer cells (sometimes referred to as cancer stem cells) drives tumor growth when transplanted into immunodeficient mice. Our objective was to identify a mouse model of breast cancer stem cells that could have relevance to the study of human breast cancer. To do so, we used breast tumors of the mouse mammary tumor virus...

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Identifiers

PMID: 17975224
DOI: 10.1634/stemcells.2007-0440

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