Article
SiDCoN: a tool to aid scoring of DNA copy number changes in SNP chip data.
PloS one - 31 Oct 2007
Nancarrow Derek J, Handoko Herlina Y, Stark Mitchell S, Whiteman David C, Hayward Nicholas K
Abstract excerpt
The recent application of genome-wide, single nucleotide polymorphism (SNP) microarrays to investigate DNA copy number aberrations in cancer has provided unparalleled sensitivity for identifying genomic changes. In some instances the complexity of these changes makes them difficult to interpret, particularly when tumour samples are contaminated with normal (stromal) tissue. Current automated scoring algorithms...
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