Article
Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays.
Genome biology - 1 Jan 2009
Popova Tatiana, Manié Elodie, Stoppa-Lyonnet Dominique, Rigaill Guillem, Barillot Emmanuel, Stern Marc Henri
Abstract excerpt
We describe a method for automatic detection of absolute segmental copy numbers and genotype status in complex cancer genome profiles measured with single-nucleotide polymorphism (SNP) arrays. The method is based on pattern recognition of segmented and smoothed copy number and allelic imbalance p...
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