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Article

Absence of keratin 19 in mice causes skeletal myopathy with mitochondrial and sarcolemmal reorganization.

Journal of cell science - 15 Nov 2007

Stone Michele R, O'Neill Andrea, Lovering Richard M, Strong John, Resneck Wendy G, Reed Patrick W, Toivola Diana M, Ursitti Jeanine A, Omary M Bishr, Bloch Robert J

Abstract excerpt

Intermediate filaments, composed of desmin and of keratins, play important roles in linking contractile elements to each other and to the sarcolemma in striated muscle. We examined the contractile properties and morphology of fast-twitch skeletal muscle from mice lacking keratin 19. Tibialis anterior muscles of keratin-19-null mice showed a small but significant decrease in mean fiber diameter and in the specific...

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Identifiers

PMID: 17971417
DOI: 10.1242/jcs.009241
PMCID: PMC9202444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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