Lack of desmin results in abortive muscle regeneration and modifications in synaptic structure.

Abstract excerpt

Desmin, a muscle-specific intermediate filament protein, is expressed in all muscle tissues. Its absence leads to a multisystemic disorder involving cardiac, skeletal, and smooth muscles. In skeletal muscle, structural abnormalities include lack of alignment of myofibrils, Z disk streaming, and focal muscle degeneration. In this study, we have examined the consequences of an absence of desmin on the mechanisms of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Adhesion Molecules, Neuronal
• Share to Desmin