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Article

Myo18b is essential for sarcomere assembly in fast skeletal muscle

18 Jan 2017

Abstract excerpt

Congenital myopathies are muscle degenerative disorders with a broad clinical spectrum. A number of myopathies have been associated with molecular defects within sarcomeres, the force-generating component of the muscle cell. Whereas the highly regular organization of the myofibril has been studied in detail, in vivo assembly of sarcomeres remains a poorly understood process. Therefore, a more detailed knowledge...

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PMID: 28104788
DOI: 10.1093/hmg/ddx025

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