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Article

Structural and functional evaluation of branched myofibers lacking intermediate filaments.

American journal of physiology. Cell physiology - 15 Jul 2012

Goodall Mariah H, Ward Christopher W, Pratt Stephen J P, Bloch Robert J, Lovering Richard M

Abstract excerpt

Intermediate filaments (IFs), composed of desmin and keratins, link myofibrils to each other and to the sarcolemma in skeletal muscle. Fast-twitch muscle of mice lacking the IF proteins, desmin and keratin 19 (K19), showed reduced specific force and increased susceptibility to injury in earlier studies. Here we tested the hypothesis that the number of malformed myofibers in mice lacking desmin (Des(-/-)), keratin...

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Identifiers

PMID: 22592402
DOI: 10.1152/ajpcell.00136.2012
PMCID: PMC3404518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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