Article
Caenorhabditis elegans exoskeleton collagen COL-19: an adult-specific marker for collagen modification and assembly, and the analysis of organismal morphology.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2003
Thein Melanie C, McCormack Gillian, Winter Alan D, Johnstone Iain L, Shoemaker Charles B, Page Antony P
Abstract excerpt
The integral role that collagens play in the morphogenesis of the nematode exoskeleton or cuticle makes them a useful marker in the examination of the collagen synthesizing machinery. In this study, a green fluorescent protein-collagen fusion has been constructed by using the Caenorhabditis elegans adult-specific, hypodermally synthesized collagen COL-19. In wild-type nematodes, this collagen marker localized to...
Topics
- Age Factors
- Alleles
- Animals
- Biomarkers
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Collagen
- Extracellular Matrix
- Gene Expression Regulation, Developmental
- Genotype
- Green Fluorescent Proteins
- Indicators and Reagents