Article
Ectopic expression of desmin in the epidermis of transgenic mice permits development of a normal epidermis.
Differentiation; research in biological diversity - 1 Mar 2002
Kirfel Jutta, Peters Bettina, Grund Christine, Reifenberg Kurt, Magin Thomas M
Abstract excerpt
Cell architecture is largely based on the interaction of cytoskeletal proteins, which include intermediate filaments (IF), microfilaments, microtubules, as well as their type-specific membrane-attachment structures and associated proteins. In order to further our understanding of IF proteins and to address the fundamental issue whether different IF perform unique functions in different tissues, we expressed a...
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