Article
The Ccr4-not complex regulates Skn7 through Srb10 kinase.
Eukaryotic cell - 1 Dec 2007
Lenssen Eve, Azzouz Nowel, Michel Agnès, Landrieux Emilie, Collart Martine A
Abstract excerpt
The Ccr4-Not complex is a multifunctional regulatory platform composed of nine subunits that controls diverse cellular events including mRNA degradation, protein ubiquitination, and transcription. In this study, we identified the yeast Saccharomyces cerevisiae osmotic and oxidative stress transcription factor Skn7 as a new target for regulation by the Ccr4-Not complex. Skn7 interacts with Not1 in a two-hybrid...
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