Article
Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.
The Journal of biological chemistry - 9 Mar 2001
Liu H Y, Chiang Y C, Pan J, Chen J, Salvadore C, Audino D C, Badarinarayana V, Palaniswamy V, Anderson B, Denis C L
Abstract excerpt
The CCR4-NOT transcriptional regulatory complex affects transcription both positively and negatively and consists of the following two complexes: a core 1 x 10(6) dalton (1 MDa) complex consisting of CCR4, CAF1, and the five NOT proteins and a larger, less defined 1.9-MDa complex. We report here the identification of two new factors that associate with the CCR4-NOT proteins as follows: CAF4, a WD40-containing...
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