Ancestral inference and the study of codon bias evolution: implications for molecular evolutionary analyses of the Drosophila melanogaster subgroup.

Abstract excerpt

Reliable inference of ancestral sequences can be critical to identifying both patterns and causes of molecular evolution. Robustness of ancestral inference is often assumed among closely related species, but tests of this assumption have been limited. Here, we examine the performance of inference methods for data simulated under scenarios of codon bias evolution within the Drosophila melanogaster subgroup. Genome...

Topics

• Animals
• Biological Evolution
• Cell Lineage
• Codon
• DNA Mutational Analysis
• Drosophila melanogaster
• Evolution, Molecular
• Genetic Variation
• Likelihood Functions
• Models, Genetic
• Mutation