Genome-wide heterogeneity of nucleotide substitution model fit.

Abstract excerpt

At a genomic scale, the patterns that have shaped molecular evolution are believed to be largely heterogeneous. Consequently, comparative analyses should use appropriate probabilistic substitution models that capture the main features under which different genomic regions have evolved. While efforts have concentrated in the development and understanding of model selection techniques, no descriptions of overall...

Topics

• Animals
• Drosophila
• Evolution, Molecular
• Genome
• Mammals
• Models, Genetic
• Mutation
• Nucleotides
• Open Reading Frames
• Phylogeny
• Sequence Alignment
• Vertebrates