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Article

Variations in intracellular levels of TATA binding protein can affect specific genes by different mechanisms.

Molecular and cellular biology - 1 Jan 2008

Bush Stephanie D, Richard Patricia, Manley James L

Abstract excerpt

We previously showed that reduced intracellular levels of the TATA binding protein (TBP), brought about by tbp heterozygosity in DT40 cells, resulted in a mitotic delay reflecting reduced expression of the mitotic regulator cdc25B but did not significantly affect overall transcription. Here we extend these findings in several ways. We first provide evidence that the decrease in cdc25B expression reflects reduced...

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Identifiers

PMID: 17954564
DOI: 10.1128/MCB.00809-07
PMCID: PMC2223301

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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