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Article

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.

Nature cell biology - 1 Nov 2007

Takada Ichiro, Mihara Masatomo, Suzawa Miyuki, Ohtake Fumiaki, Kobayashi Shinji, Igarashi Mamoru, Youn Min-Young, Takeyama Ken-ichi, Nakamura Takashi, Mezaki Yoshihiro, Takezawa Shinichiro, Yogiashi Yoshiko, Kitagawa Hirochika, Yamada Gen, Takada Shinji, Minami Yasuhiro, Shibuya Hiroshi, Matsumoto Kunihiro, Kato Shigeaki

Abstract excerpt

Histone modifications induced by activated signalling cascades are crucial to cell-lineage decisions. Osteoblast and adipocyte differentiation from common mesenchymal stem cells is under transcriptional control by numerous factors. Although PPAR-gamma (peroxisome proliferator activated receptor-gamma) has been established as a prime inducer of adipogenesis, cellular signalling factors that determine cell lineage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17952062
DOI: 10.1038/ncb1647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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