Article
Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation
1 Jan 2013
Abstract excerpt
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and adipogenic lineage commitment and differentiation, a theoretical inverse relationship exists, such that differentiation towards an osteoblast phenotype occurs at the expense of an adipocytic phenotype. This balance is regulated by...
Topics
Join the communities discussing this publication.