Article
Genetic and epigenetic regulation of PPARγ during adipogenesis.
Yi chuan = Hereditas - 20 Nov 2017
Cui Ting-Ting, Xing Tian-Yu, Chu Yan-Kan, Li Hui, Wang Ning
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis and adipose tissue development. It also plays crucial roles in many other biological processes, including lipid and glucose metabolism and energy homeostasis. Recently, evidence has been accumulating that the PPARγ gene is not only genetically regulated, but also epigenetically regulated by DNA methylation, histone...
Topics
- Adipogenesis
- Animals
- Chromatin Assembly and Disassembly
- DNA Methylation
- Histones
- Humans
- PPAR gamma
- Polymorphism, Single Nucleotide
