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Article

Targeted inhibition of Pdp1epsilon abolishes the circadian behavior of Drosophila melanogaster.

Biochemical and biophysical research communications - 14 Dec 2007

Lim Chunghun, Lee Jongbin, Koo Eunjin, Choe Joonho

Abstract excerpt

vrille and Par domain protein 1 (Pdp1) epsilon constitute the second transcriptional feedback loop in Drosophila circadian clock system. Their rhythmic expression is controlled by Drosophila Clock (dClk) gene, and they feed back to negatively and positively, respectively, regulate the oscillating transcription from dClk gene. In this study, we characterized the functional domains of PDP1epsilonin vitro using a...

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Source

Identifiers

PMID: 17950247
DOI: 10.1016/j.bbrc.2007.10.009

Genes

PDP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeted inhibition of Pdp1epsilon abolishes the circadian behavior of Drosophila melanogaster.PMID 17950247Read ↗

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