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Article

Replication study and meta-analysis of the genetic association of GRM3 gene polymorphisms with schizophrenia in a large Japanese case-control population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2008

Albalushi Talal, Horiuchi Yasue, Ishiguro Hiroki, Koga Minori, Inada Toshiya, Iwata Nakao, Ozaki Norio, Ujike Hiroshi, Watanabe Yuichiro, Someya Toshiyuki, Arinami Tadao

Abstract excerpt

The GRM3 gene, which encodes a metabotropic glutamate receptor, is an important candidate gene for susceptibility to schizophrenia. Two single nucleotide polymorphisms (SNPs), rs1468412 and rs2299225 in intron 3, were reported to be associated with schizophrenia in Japanese and Chinese populations, respectively. Haplotypes with these SNPs were also reported to be associated with schizophrenia. In the present...

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Source

Identifiers

PMID: 17948896
DOI: 10.1002/ajmg.b.30610

Genes

GRM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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