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Article

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle.

The Journal of clinical investigation - 1 Nov 2007

Ling Charlotte, Poulsen Pernille, Simonsson Stina, Rönn Tina, Holmkvist Johan, Almgren Peter, Hagert Per, Nilsson Emma, Mabey Amanda G, Nilsson Peter, Vaag Allan, Groop Leif

Abstract excerpt

Insulin resistance and type 2 diabetes are associated with decreased expression of genes that regulate oxidative phosphorylation in skeletal muscle. To determine whether this defect might be inherited or acquired, we investigated the association of genetic, epigenetic, and nongenetic factors with expression of NDUFB6, a component of the respiratory chain that is decreased in muscle from diabetic patients....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17948130
DOI: 10.1172/JCI30938
PMCID: PMC2030455

Genes

NDUFB6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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