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Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism

2021-03-17

Abstract excerpt

Nearly all human complex traits and diseases exhibit some degree of sex differences, with epigenetics being one of the main contributing factors. Various tissues display sex differences in DNA methylation, however this has not yet been explored in skeletal muscle, despite skeletal muscle being among the tissues with the most transcriptomic sex differences. For the first time, we investigated the effect of sex on a...

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Literature Corpus work
dcce0e35-28b7-5b66-9d7a-ddec77cbf564
DOI
10.1101/2021.03.16.435733
Open publication

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Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolismDOI 10.1101/2021.03.16.435733
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