Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Soluble CD44 secretion contributes to the acquisition of aggressive tumor phenotype in human colon cancer cells.

Experimental and molecular pathology - 1 Dec 2007

Subramaniam Venkateswaran, Gardner Helena, Jothy Serge

Abstract excerpt

CD44, a widely distributed cell surface glycoprotein and a receptor for hyaluronan (HA), has been implicated in facilitating tumor growth and metastasis, antiapoptosis and directional motility of cancer cells. In order to investigate the role of soluble CD44 (CD44(sol)) in colon cancer cell growth, SW620, a human colon cancer cell line deficient in CD44 expression was stably transfected with human CD44 cDNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Adhesion
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Colonic Neoplasms

Share to Hyaluronan Receptors

Share to Hyaluronic Acid

Source

Identifiers

PMID: 17945213
DOI: 10.1016/j.yexmp.2007.08.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Soluble CD44 secretion contributes to the acquisition of aggressive tumor phenotype in human colon cancer cells.PMID 17945213Read ↗

CD44: A Multifunctional Mediator of Cancer ProgressionSemantic proximity Read ↗

Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell markerSemantic proximity Read ↗

The v8-10 variant isoform of CD44 is selectively expressed in the normal human colonic stem cell niche and frequently is overexpressed in colon carcinomas during tumor developmentSemantic proximity Read ↗

CD44 as a potential diagnostic tumor markerSemantic proximity Read ↗

CD44 and its implication in neoplastic diseasesSemantic proximity Read ↗

CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer CellsSemantic proximity Read ↗

The normal structure and function of CD44 and its role in neoplasiaSemantic proximity Read ↗

CD44 promotes resistance to apoptosis in human colon cancer cellsSemantic proximity Read ↗

The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7Semantic proximity Read ↗

Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3.Semantic proximity Read ↗

Identification and phenotypic characterization of a subpopulation of T84 human colon cancer cells, after selection on activated endothelial cells.Semantic proximity Read ↗

IL-8/CXCR2 mediates tropism of human bone marrow-derived mesenchymal stem cells toward CD133+ /CD44+ Colon cancer stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.