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Article

The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7

12 Jul 2011

Abstract excerpt

BACKGROUND: CD44, a hyaluronan (HA) receptor, is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival. The CD44 gene contains 20 exons that are...

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PMID: 21749678
DOI: 10.1186/1471-2407-11-290

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