Article
Identification and phenotypic characterization of a subpopulation of T84 human colon cancer cells, after selection on activated endothelial cells.
Journal of cellular physiology - 1 Apr 2005
Alessandro R, Flugy A M, Russo D, Stassi G, De Leo A, Corrado C, Alaimo G, De Leo G
Abstract excerpt
The extravasation of metastatic cells is regulated by molecular events involving the initial adhesion of tumor cells to the endothelium and subsequently the migration of the cells in the host connective tissue. The differences in metastatic ability could be attributed to properties intrinsic of the various primary tumor types. Thus, the clonal selection of neoplastic cells during cancer progression results in...
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