Article
Two C. elegans genes control the programmed deaths of specific cells in the pharynx.
Development (Cambridge, England) - 1 Jun 1991
Ellis R E, Horvitz H R
Abstract excerpt
The genes ces-1 and ces-2 control the decisions of two cells in the nematode Caenorhabditis elegans to undergo programmed cell death. Mutations that cause a gain of ces-1 function or a reduction of ces-2 function prevent these cells, the sisters of the two pharyngeal NSM neurons, from dying. These mutations do not affect most other cell deaths. Genetic studies indicate that ces-1 and ces-2 affect the fates of the...
Topics
- Animals
- Caenorhabditis
- Cell Survival
- Chromosome Mapping
- Genes, Regulator
- Genotype
- Mutagenesis
- Pharynx
- Phenotype