Article
Two C. elegans genes control the programmed deaths of specific cells in the pharynx.
Development (Cambridge, England) - 1 Jun 1991
Ellis R E, Horvitz H R
Abstract excerpt
The genes ces-1 and ces-2 control the decisions of two cells in the nematode Caenorhabditis elegans to undergo programmed cell death. Mutations that cause a gain of ces-1 function or a reduction of ces-2 function prevent these cells, the sisters of the two pharyngeal NSM neurons, from dying. These mutations do not affect most other cell deaths. Genetic studies indicate that ces-1 and ces-2 affect the fates of the...
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