Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans.

Developmental biology - 1 Oct 2004

Hoeppner Daniel J, Spector Mona S, Ratliff Thomas M, Kinchen Jason M, Granat Susan, Lin Shih-Chieh, Bhusri Satjit S, Conradt Barbara, Herman Michael A, Hengartner Michael O

Abstract excerpt

Programmed cell death occurs in every multicellular organism and in diverse cell types yet the genetic controls that define which cells will live and which will die remain poorly understood. During development of the nematode Caenorhabditis elegans, the coordinated activity of four gene products, EGL-1, CED-9, CED-4 and CED-3, results in the death of essentially all cells fated to die. To identify novel upstream...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Green Fluorescent Proteins

Share to Luminescent Proteins

Share to Neurons

Share to Repressor Proteins

Share to Sequence Alignment

Source

Identifiers

PMID: 15355793
DOI: 10.1016/j.ydbio.2004.06.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans.PMID 15355793Read ↗

Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans.Semantic proximity Read ↗

Programmed cell deathSemantic proximity Read ↗

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene.Semantic proximity Read ↗

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germlineSemantic proximity Read ↗

The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9.Semantic proximity Read ↗

Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons.Semantic proximity Read ↗

The ins and outs of programmed cell death during C. elegans development.Semantic proximity Read ↗

Control of nonapoptotic developmental cell death in Caenorhabditis elegans by a polyglutamine-repeat protein.Semantic proximity Read ↗

Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho.Semantic proximity Read ↗

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans.Semantic proximity Read ↗

Noncanonical cell death programs in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

A Genome-Wide RNAi Screen for Factors Involved in Neuronal Specification in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.