Article
Arp2/3-independent assembly of actin by Vibrio type III effector VopL.
Proceedings of the National Academy of Sciences of the United States of America - 23 Oct 2007
Liverman Amy D B, Cheng Hui-Chun, Trosky Jennifer E, Leung Daisy W, Yarbrough Melanie L, Burdette Dara L, Rosen Michael K, Orth Kim
Abstract excerpt
Microbial pathogens use a variety of mechanisms to disrupt the actin cytoskeleton during infection. Vibrio parahaemolyticus (V. para) is a Gram-negative bacterium that causes gastroenteritis, and new pandemic strains are emerging throughout the world. Analysis of the V. para genome revealed a type III secretion system effector, VopL, encoding three Wiskott-Aldrich homology 2 domains that are interspersed with...
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