Article
Intestinal Ca2+ wave dynamics in freely moving C. elegans coordinate execution of a rhythmic motor program.
American journal of physiology. Cell physiology - 1 Jan 2008
Nehrke K, Denton Jerod, Mowrey William
Abstract excerpt
Defecation in the nematode worm Caenorhabditis elegans is a highly rhythmic behavior that is regulated by a Ca(2+) wave generated in the 20 epithelial cells of the intestine, in part through activation of the inositol 1,4,5-trisphosphate receptor. Execution of the defecation motor program (DMP) can be modified by external cues such as nutrient availability or mechanical stimulation. To address the likelihood that...
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