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Article

Long-term monitoring of Ca2+ dynamics in C. elegans pharynx: an in vivo energy balance sensor.

Oncotarget - 18 Oct 2016

Alvarez-Illera Pilar, Sanchez-Blanco Adolfo, Lopez-Burillo Silvia, Fonteriz Rosalba I, Alvarez Javier, Montero Mayte

Abstract excerpt

Ca2+ is a key signal transducer for muscle contraction. Continuous in vivo monitoring of intracellular Ca2+-dynamics in C. elegans pharynx muscle revealed surprisingly complex Ca2+ patterns. Despite the age-dependent decline of pharynx pumping, we observed unaltered fast Ca2+ oscillations both in young and old worms. In addition, sporadic prolonged Ca2+ increases lasting many seconds or minutes were often...

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Identifiers

PMID: 27661127
DOI: 10.18632/oncotarget.12177
PMCID: PMC5356515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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