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Article

The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.

Cell - 17 Sept 1999

Dal Santo P, Logan M A, Chisholm A D, Jorgensen E M

Abstract excerpt

The C. elegans defecation cycle is characterized by the contraction of three distinct sets of muscles every 50 s. Our data indicate that this cycle is regulated by periodic calcium release mediated by the inositol trisphosphate receptor (IP3 receptor). Mutations in the IP3 receptor slow down or eliminate the cycle, while overexpression speeds up the cycle. The IP3 receptor controls these periodic muscle...

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PMID: 10499793
DOI: 10.1016/s0092-8674(00)81510-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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