Article
FLR-4, a novel serine/threonine protein kinase, regulates defecation rhythm in Caenorhabditis elegans.
Molecular biology of the cell - 1 Mar 2005
Take-uchi Masaya, Kobayashi Yuri, Kimura Koutarou D, Ishihara Takeshi, Katsura Isao
Abstract excerpt
The defecation behavior of the nematode Caenorhabditis elegans is controlled by a 45-s ultradian rhythm. An essential component of the clock that regulates the rhythm is the inositol trisphosphate receptor in the intestine, but other components remain to be discovered. Here, we show that the flr-4 gene, whose mutants exhibit very short defecation cycle periods, encodes a novel serine/threonine protein kinase with...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calcium Channels
- Circadian Rhythm
- Cloning, Molecular
- DNA, Complementary
- Defecation
- Gene Expression Regulation, Developmental