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Article

FLR-4, a novel serine/threonine protein kinase, regulates defecation rhythm in Caenorhabditis elegans.

Molecular biology of the cell - 1 Mar 2005

Take-uchi Masaya, Kobayashi Yuri, Kimura Koutarou D, Ishihara Takeshi, Katsura Isao

Abstract excerpt

The defecation behavior of the nematode Caenorhabditis elegans is controlled by a 45-s ultradian rhythm. An essential component of the clock that regulates the rhythm is the inositol trisphosphate receptor in the intestine, but other components remain to be discovered. Here, we show that the flr-4 gene, whose mutants exhibit very short defecation cycle periods, encodes a novel serine/threonine protein kinase with...

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Identifiers

PMID: 15647385
DOI: 10.1091/mbc.e04-04-0273
PMCID: PMC551498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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