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Article

Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 21 Oct 2008

Mahoney Timothy R, Luo Shuo, Round Elaine K, Brauner Martin, Gottschalk Alexander, Thomas James H, Nonet Michael L

Abstract excerpt

The Caenorhabditis elegans defecation motor program (DMP) is a highly coordinated rhythmic behavior that requires two GABAergic neurons that synapse onto the enteric muscles. One class of DMP mutants, called anterior body wall muscle contraction and expulsion defective (aex) mutants, exhibits similar defects to those caused by the loss of these two neurons. Here, we demonstrate that aex-2 encodes a...

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Identifiers

PMID: 18852466
DOI: 10.1073/pnas.0803617105
PMCID: PMC2570992

Genes

SNAP25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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