Article
Genetic dissection of ion currents underlying all-or-none action potentials in C. elegans body-wall muscle cells.
The Journal of physiology - 1 Jan 2011
Liu Ping, Ge Qian, Chen Bojun, Salkoff Lawrence, Kotlikoff Michael I, Wang Zhao-Wen
Abstract excerpt
Although the neuromuscular system of C. elegans has been studied intensively, little is known about the properties of muscle action potentials (APs). By combining mutant analyses with in vivo electrophysiological recording techniques and Ca2+ imaging, we have established the fundamental properties and molecular determinants of body-wall muscle APs. We show that, unlike mammalian skeletal muscle APs, C. elegans...
Topics
- Action Potentials
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calcium Channels
- Calcium Channels, T-Type
- Excitation Contraction Coupling
- Ion Channels
- Membrane Transport Proteins
- Motor Neurons
- Muscle Cells
- Muscle Proteins
- Muscles