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Article

Selenium in mammalian spermiogenesis

1 Oct 2007

Abstract excerpt

The role of selenium in male fertility is reviewed with special emphasis on selenoprotein P and phospholipid hydroperoxide glutathione peroxidase (GPx4) in spermiogenesis. Inverse genetics reveal that selenoprotein P is required for selenium supply to the testis. GPx4 is abundantly synthesized in spermatids. As a moonlighting protein it is transformed in the later stages of spermiogenesis from an active...

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PMID: 17937612
DOI: 10.1515/bc.2007.112

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