Article
Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Aug 1991
Sommers C L, Thompson E W, Torri J A, Kemler R, Gelmann E P, Byers S W
Abstract excerpt
Loss of cell-cell adhesion in carcinoma cells may be an important step in the acquisition of an invasive, metastatic phenotype. We have examined the expression of the epithelial-specific cell adhesion molecule uvomorulin (E-cadherin, cell-CAM 120/80, L-CAM) in human breast cancer cell lines. We find that fibroblastoid, highly invasive, vimentin-expressing breast cancer cell lines do not express uvomorulin. Of the...
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