Article
Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Aug 1991
Sommers C L, Thompson E W, Torri J A, Kemler R, Gelmann E P, Byers S W
Abstract excerpt
Loss of cell-cell adhesion in carcinoma cells may be an important step in the acquisition of an invasive, metastatic phenotype. We have examined the expression of the epithelial-specific cell adhesion molecule uvomorulin (E-cadherin, cell-CAM 120/80, L-CAM) in human breast cancer cell lines. We f...
Topics
- Blotting, Northern
- Breast Neoplasms
- Cadherins
- Chemotaxis
- Collagen
- Drug Combinations
- Extracellular Matrix
- Gene Expression
- Humans
- Laminin
- Microscopy, Fluorescence
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Phenotype
- Proteoglycans
- RNA, Messenger
- RNA, Neoplasm
- Tumor Cells, Cultured