Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line.

doi:10.1038/bjc.1995.52

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Article

Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line.

British journal of cancer - 1 Feb 1995

Shiozaki H, Kadowaki T, Doki Y, Inoue M, Tamura S, Oka H, Iwazawa T, Matsui S, Shimaya K, Takeichi M

Abstract excerpt

Epidermal growth factor (EGF) mediates many pleiotrophic biological effects, one of which is alteration of cellular morphology. In the present study, we examine the possibility that this alteration in cell morphology is caused in part by the dysfunction of cadherin-mediated cell-cell adhesion using the human oesophageal cancer cell line TE-2R, which expresses E-cadherin and EGF receptor. In the presence of EGF,...

Topics

Benzoquinones
Cadherins
Carcinoma, Squamous Cell
Cell Adhesion
Cell Aggregation
Cell Line
Culture Techniques
Cytoskeletal Proteins
Epidermal Growth Factor
ErbB Receptors
Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fibroblasts

Fluorescent Antibody Technique

Gels

Humans

Lactams, Macrocyclic

Neoplasm Invasiveness

Neoplasm Proteins

Source

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Identifiers

PMID: 7530982
DOI: 10.1038/bjc.1995.52
PMCID: PMC2033604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7530982-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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