Article
An entropy-based measure for QTL mapping using extreme samples of population.
Human heredity - 1 Jan 2008
Li Yu-Mei, Xiang Yang, Sun Zhen-Qiu
Abstract excerpt
Quantitative trait locus (QTL) mapping can be accomplished through the method of selective genotyping, which is based on the differences of frequencies between an upper sample and a lower sample in population. However, amplifying the differences in marker allele frequencies in extreme samples may increase the probability for QTL mapping. Shannon entropy, which is a nonlinear function of allele frequencies, can be...
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