Article
Entropy based genetic association tests and gene-gene interaction tests.
Statistical applications in genetics and molecular biology - 22 Aug 2011
de Andrade Mariza, Wang Xin
Abstract excerpt
In the past few years, several entropy-based tests have been proposed for testing either single SNP association or gene-gene interaction. These tests are mainly based on Shannon entropy and have higher statistical power when compared to standard χ2 tests. In this paper, we extend some of these tests using a more generalized entropy definition, Rényi entropy, where Shannon entropy is a special case of order 1. The...
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