Article
An adaptive strategy for association analysis of common or rare variants using entropy theory.
Journal of human genetics - 1 Aug 2017
Li Yu-Mei, Xu Chao, Xiang Yang, Peng Cheng, Deng Hong-Wen
Abstract excerpt
Advances in DNA sequencing technology have been promoting the development of sequencing studies to identify rare variants associated with complex traits. Adaptive strategy can be effective to reduce the noise provided by non-causal variants. However, the existing adaptive strategies depend on many assumptions. In this paper, we proposed a new adaptive strategy using entropy theory for association analysis. This...
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