Article
Entropy-based joint analysis for two-stage genome-wide association studies.
Journal of human genetics - 1 Jan 2007
Kang Guolian, Zuo Yijun
Abstract excerpt
Genome-wide association studies (GWAS) are being conducted to identify common genetic variants that predispose to human diseases to unravel the genetic etiology of complex human diseases now. Because of genotyping cost constraints, it often follows a two-stage design, in which a large number of markers are identified in a proportion of the available samples in stage 1, and then the markers identified in stage 1...
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